Multimodal prognostication of autoimmune encephalitis: an Australian autoimmune encephalitis consortium study.

ABSTRACT:

Background and objectives

To identify factors predictive of a favourable modified Rankin score (mRS) at 12 months in patients with autoimmune encephalitis (AE). To evaluate predictors of a binary composite clinical-functional outcome measure, encompassing mRS, drug-resistant epilepsy (DRE) and memory impairment, at 12 months.

Methods

Univariable and multivariable logistic regression analyses for predictors of a favourable mRS (i.e. mRS ≤ 2) and a composite clinical-functional outcome at 12 months were used.

Results

A total of 231 patients with AE were recruited. Multivariable logistic regression identified factors predictive of reduced odds of favourable mRS at 12 months were older age (OR 0.97; 95% CI 0.95, 0.98; p < 0.001), T2/FLAIR hyperintensity on initial MRI (OR

SUBMITTER: Seery N 

PROVIDER: S-EPMC12031909 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature