A comparison of health-related quality of life between continuous ambulatory peritoneal dialysis and automated peritoneal dialysis in children with stage 5 chronic kidney disease in Thailand: a randomized controlled trial.

ABSTRACT:

Background

Improving health-related quality of life (HRQoL) is one of the main goals in managing stage 5 chronic kidney disease (CKD). However, limited evidence compares HRQoL between continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) in children. This open-label randomized controlled trial (RCT) aimed to compare HRQoL in pediatric patients with stage 5 CKD receiving CAPD vs. APD in Thailand.

Methods

Children with stage 5 CKD were randomized 1:1 to receive APD or CAPD. The primary outcome was HRQoL, measured by EQ-5D-5L, EQ-5D-3L, and PedsQL at baseline, week 16 and week 48. Outcomes were analyzed using linear mixed models.

Results

A total of 60 patients were recruited: 30 with CAPD and 30 with APD. General characteristics, utilit

SUBMITTER: Thavorncharoensap M 

PROVIDER: S-EPMC12031995 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature