Genetic diversity of Ancylostoma ceylanicum and first molecular detection of Ancylostoma braziliense in stray dogs from Sarawak, Malaysia.

ABSTRACT: Hookworms are blood-sucking intestinal parasites that can cause anaemia and protein loss in humans. Ancylostoma ceylanicum, a zoonotic hookworm species of dogs, is the second most common cause of human hookworm infections. With the increasing anthelmintic resistance risks and the uncontrolled stray dog population in Sarawak Borneo, East Malaysia, understanding the genetic structure of A. ceylanicum is crucial for tracking mutation patterns and assessing zoonotic transmission risks. This study determined the prevalence and genetic diversity of dog hookworm species using microscopy, PCR and sequencing, revealing A. ceylanicum (43.6%; 89/204), followed by mixed infections of A. ceylanicum and A. braziliense (9.3%; 19/204), single infections of A. caninum (6.3%; 13/204), and A. braziliense (1.

SUBMITTER: Tahar AS 

PROVIDER: S-EPMC12032019 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature