Establishment and genetic characterization of zebrafish RW line.

ABSTRACT: Zebrafish have emerged as an alternative vertebrate model for both basic and applied science. While two zebrafish lines, AB and TU, have been extensively used, recent studies suggest that complex behaviors and susceptibility to adult phenotypes vary among lines. Given the increasing demand across diverse research fields, establishing a phylogenetically distinct wild-type zebrafish line without deleterious genetic variants would greatly benefit the research community. In this study, we documented the establishment of the RIKEN Wild-type (RW) line and conducted comparative genome analyses to investigate the genetic characteristics of various wild-type zebrafish lines such as AB, TU, TL, WIK, SAT, NHGRI-1, PET, *AB, IND, M-AB and IM with a particular focus on the genetic characterization of t

SUBMITTER: Sadamitsu K 

PROVIDER: S-EPMC12032133 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature