Nomogram for Predicting Hemorrhagic Transformation Risk in Acute Ischemic Stroke Patients With Atrial Fibrillation.

ABSTRACT:

Background

Hemorrhagic transformation (HT) is a critical complication in acute ischemic stroke (AIS) patients with atrial fibrillation (AF) awaiting anticoagulation reinitiation. No reliable predictive model exists for assessing HT risk for these patients. Clinical decisions typically rely on NIHSS score and infarct size; however, other relevant risk factors remain insufficiently explored. This study aimed to develop and validate a predictive model for assessing the risk of HT in AIS patients with AF from stroke onset to anticoagulation therapy reinitiation.

Methods

This retrospective study included AIS patients with AF from two comprehensive medical centers in China. The primary outcome was HT postinfarction confirmed with CT/MRI before anticoagulation reinitiation. Signifi

SUBMITTER: Chen J 

PROVIDER: S-EPMC12032400 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature