Improving sustainable isopropanol production in engineered Escherichia coli W via oxygen limitation.

ABSTRACT:

Background

Due to ecological concerns, alternative supply lines for fuel and bulk chemicals such as isopropanol are increasingly pursued. By implementing the formation pathways from natural producers like Clostridium beijerinckii and Clostridium aurantibutyricum, isopropanol can be produced in Escherichia coli. However, developing an industrially and economically feasible microbial production process requires a robust and efficient process strategy. Therefore, this study explores microaerobic conditions in combination with lactose and sour whey as sustainable carbon source as a basis for large-scale microbial isopropanol production.

Results

Different gas-liquid mass transfer regimes (affected by variations of the stirrer speed and ingas oxygen concentration) allowed the impl

SUBMITTER: Kutscha R 

PROVIDER: S-EPMC12032697 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature