Cytosolic fructose - an underestimated player in the regulation of sucrose biosynthesis.

ABSTRACT:

Background

Plants must continuously adapt to environmental fluctuations, which significantly influence their photosynthetic performance and overall metabolism. The sucrose cycling system within plant cells plays a critical regulatory role during stress conditions. This study employed a systems biology approach to analyze system stabilities mathematically under various regulatory conditions impacting sucrose cycling dynamics. We investigated the effects of mutations within this cycle, specifically HEXOKINASE1 (Arabidopsis thaliana gin2-1), alongside high-light exposure. Finally, we confirmed the modeling output in vitro by enzyme assays.

Results

The implementation of experimental subcellular metabolite data into a Structural Kinetic Model (SKM) enabled exploration of regulato

SUBMITTER: Giesbrecht O 

PROVIDER: S-EPMC12032757 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature