Exploring the real-world experience of abemaciclib treatment for HR +, HER2 - metastatic breast cancer-a qualitative analysis of the IMPACTOR study.

ABSTRACT:

Purpose

The IMPACTOR study (IMPact of AbemaCiclib on patienTs' rOles and Responsibilities-ISRCTN17281696) was developed to capture experiences of women with MBC being treated with abemaciclib in a real-world setting. The primary aim was to explore changes to quality of life over time and our secondary aim was to understand these changes in detail via qualitative interviews, as presented here.

Methods

A singular interview was offered to participants who had expressed an interest at the point of consent. These were all conducted remotely using a semi-structured interview topic guide.

Results

Twenty interviews were completed and analysed using a framework approach to thematic analysis. Eight themes were developed-COVID-19, experience of MBC, side effects, side effect man

SUBMITTER: Starkings R 

PROVIDER: S-EPMC12033103 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature