Inconsistent Reporting of Interactions Between Warfarin and Medicinal Plants Across Clinical Decision Support Resources.

ABSTRACT: BackgroundWarfarin, a commonly used anticoagulant, interacts with medicinal plants, potentially complicating patient management. Clinical Decision Resources (CDRs) provide guidance on these interactions, but inconsistencies across resources may impact clinical decisions. This study aims to evaluate the consistency of interaction reports between warfarin and medicinal plants across four online CDRs.MethodsA cross-sectional study was conducted. Medicinal plants assessed were selected from the World Health Organization's Phytotherapy Manual. Interaction reports were manually reviewed across four CDRs: UpToDate, ClinicalKey, DynaMed, and DrugBank. Interactions were categorized by severity as mild, moderate or severe.ResultsOf 141 medicinal plants reviewed, 28 were documented as interacting wit

SUBMITTER: Uribe-Cavero LJ 

PROVIDER: S-EPMC12033581 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature