A carbon nanotube/pyrrolidonecarboxylic acid zinc sponge for programmed management of diabetic wounds: Hemostatic, antibacterial, anti-inflammatory, and healing properties.

ABSTRACT: Wound healing in patients with diabetes is challenging because of chronic inflammation, inadequate vascularization, and susceptibility to infection. Current wound dressings often target specific stages of healing and lack comprehensive therapeutic approaches. This study introduces a novel approach using a photodetachable sponge scaffold incorporating carbon nanotubes (CNTs), known for their high photothermal conversion efficiency, electrical conductivity, and water absorption properties. The scaffold incorporated pyrrolidonecarboxylic acid zinc (PC₁Z₂), a compound with anti-inflammatory and moisturizing properties, which was cross-linked within a network of CNTs and a decellularized dermal matrix. The resulting shape-memory sponge scaffold actively interfaces with end

SUBMITTER: Wu C 

PROVIDER: S-EPMC12033991 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature