SHRs, biomarkers for dysregulated stress response, predict prognosis in sepsis patients: a retrospective cohort study from MIMIC-IV database.

ABSTRACT:

Background

The dysregulated stress response is a key pathological mechanism underlying sepsis and is strongly associated with poor clinical outcomes. Stress hyperglycemia, a common manifestation of this response, may provide valuable prognostic information in sepsis patients. The stress hyperglycemia ratio (SHR) offers a more accurate reflection of the stress response and may be instrumental in assessing sepsis prognosis.

Methods

This study aimed to investigate the relationship between SHRs and clinical outcomes in sepsis patients. Data were obtained from the Medical Information Mart for Intensive Care IV database. Demographic information, intensive care unit (ICU) parameters within the first 24 h, laboratory results, insulin administration, survival time, and outcomes were

SUBMITTER: Lian H 

PROVIDER: S-EPMC12034187 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature