Integrated analysis of transcriptomics and metabolomics and high-throughput amplicon sequencing reveals the synergistic effects of secondary metabolites and rhizosphere microbiota on root rot resistance in <i>Psammosilene tunicoides</i>.

ABSTRACT: Psammosilene tunicoides is a plant with significant medicinal and ecological value, exhibiting remarkable medicinal properties, particularly in anti-inflammatory, antioxidant, and immune-regulatory effects. Root rot is one of the primary diseases affecting Psammosilene tunicoides, leading to a significant decline in its quality. In this study, we utilized an integrated analysis of transcriptomics, metabolomics, high-throughput amplicon sequencing, and culturomics for revealing the difference of healthy samples (CH) and diseased samples (CD) and studying the defense mechanism of P. tunicoides in resisting root rot. Transcriptome revealed distinct patterns of gene expression between healthy root samples (HR) and diseased root samples (DR) of P. tunicoides. The Key

SUBMITTER: Yingtao L 

PROVIDER: S-EPMC12034638 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature