Atopic dermatitis and lymphoma risk: a systematic review and meta-analysis.

ABSTRACT:

Background

The relationship between atopic dermatitis (AD) and lymphoma risk remains debate. This study systematically evaluates lymphoma risk in AD patients compared to non-AD individuals.

Methods

A systematic search of PubMed, Embase, and the Cochrane Library (up to August 11, 2024) identified observational studies reporting lymphoma risk estimates for AD patients. Pooled odds ratios (OR) or relative risks (RR) with 95% CIs were calculated using a random-effects model (PROSPERO ID: CRD42024577019).

Results

Of 2,366 articles were screened, 13 studies met the inclusion criteria. AD was significantly associated with elevated lymphoma risk (OR = 2.56, 95% CI: 1.75-3.74, P < 0.001; RR = 1.23, 95% CI: 1.15-1.31, P < 0.001). The risk increased with AD severity, with severe

SUBMITTER: Tian Y 

PROVIDER: S-EPMC12034737 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature