Discordant Results Between Creatinine- and Cystatin C-based Equations for Estimating GFR.

ABSTRACT:

Introduction

Discordant results between cystatin C and creatinine in estimating glomerular filtration rate (GFR) are an important medical issue. However, the equation that should be used when GFR estimates are discordant remains unclear.

Methods

This cross-sectional analysis included 15,485 participants with GFR measured by the clearance of an exogenous marker, serum creatinine, and cystatin C. We studied the proportion of discordant results defined as an absolute (> 15 ml/min per 1.73 m²) or relative (> 20%) difference between creatinine-based estimated GFR (eGFR, eGFR_crea) and cystatin C-based eGFR (eGFR_cys) using different equations (Chronic Kidney Disease Epidemiology Collaboration [CKD-EPI], European Kidney Function Consortium [EKFC], an

SUBMITTER: Delanaye P 

PROVIDER: S-EPMC12034923 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature