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Relationship of cranial bone signal intensity to multiple sclerosis clinical course and progression.


ABSTRACT: ObjectivesMultiple sclerosis (MS) usually relapses, about half become progressive after a period of time, few are progressive from the onset. Leptomeningeal ectopic lymphoid follicles with cell flow from the cranial bone marrow may be associated with progression. The aim of this retrospective study was to determine the predictive value of cranial bone signal intensity and to correlate it with other clinical features.MethodsRetrospective clinical and radiological characteristics of 96 MS patients (16 primary progressive multiple sclerosis, 80 relapsing-remitting multiple sclerosis (RRMS)) and 60 controls (tension-type headache) were recorded. Frontal (F), occipital (O), clivus (C) and vitreous body (V) signal intensities were measured. The relationship between clinical features, disease cou

SUBMITTER: Sarıdas F 

PROVIDER: S-EPMC12035394 | biostudies-literature | 2025 Apr-Jun

REPOSITORIES: biostudies-literature