Risk of bias tools for medication adherence research: RoBIAS and RoBOAS.

ABSTRACT:

Aims

An unbiased means of documenting medication-taking is important to ensure quality evidence about adherence research and to accurately identify individuals at risk of suboptimal adherence for the development of targeted and effective interventions. Guidance to assist researchers in the understanding of risk of bias when conducting or reviewing adherence research is currently not available. To address this gap, tools to identify and gauge the magnitude of important biases that may impact adherence research have been developed.

Methods

The Risk of Bias tool for Interventional Adherence Studies (RoBIAS) and the Risk of Bias tool for Observational Adherence Studies (RoBOAS) were constructed from a literature review of key adherence guidelines/frameworks, drafted initially th

SUBMITTER: Sinnappah KA 

PROVIDER: S-EPMC12035589 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature