FMRFamide-like peptides (FaLPs) - an overview of diverse physiological roles in insects and other arthropods.

ABSTRACT: FMRFamide-like peptides (FaLPs) are neuropeptides that play a pivotal role in regulating various physiological processes in insects and other arthropods including behaviour, reproduction, and homeostasis. FaLPs mostly act through G-protein coupled receptor and influence muscle activity by modulating Ca²⁺ influx. Historically, the function described for these neuropeptides was primarily associated with myostimulatory activity. After more than three decades of research, it is now well established that FaLPs are implicated in the regulation of circadian rhythms, affecting locomotor activity and phase changes in response to environmental cues. During reproduction, FaLPs influence contractile activity in both the male and female reproductive systems. They also participate in physiolo

SUBMITTER: Chowanski S 

PROVIDER: S-EPMC12035899 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature