Association of insulin resistance indices with kidney stones and their recurrence in a non-diabetic population: an analysis based on NHANES data from 2007-2018.

ABSTRACT:

Objective

To systematically evaluate the association between insulin resistance indices and the risk of kidney stones and their recurrence in U.S. non-diabetic individuals, while identifying predictive indicators.

Materials and methods

This cross-sectional study analyzed data from the 2007-2018 NHANES. Five IR indices were calculated. Weighted logistic regression, restricted cubic spline, and mediation analyses were used to assess the independent associations between these indices and the risk of kidney stones and recurrence in non-diabetic individuals.

Result

This study of 9,605 non-diabetic participants showed an overall kidney stones incidence of 8.63% and a recurrence rate of 2.70%. Weighted logistic regression and RCS analyses revealed significant positive associ

SUBMITTER: Yang YX 

PROVIDER: S-EPMC12035944 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature