Recombination and transposition drive genomic structural variation potentially impacting life history traits in a host-generalist fungal plant pathogen.

ABSTRACT:

Background

An understanding of plant pathogen evolution is important for sustainable management of crop diseases. Plant pathogen populations must maintain adequate heritable phenotypic variability to survive. Polymorphisms ≥ 50 bp, known as structural variants (SVs), could contribute strongly to this variability by disrupting gene activities. SV acquisition is largely driven by mobile genetic elements called transposons, though a less appreciated source of SVs is erroneous meiotic double-strand break repair. The relative impacts of transposons and recombination on SV diversity and the overall contribution of SVs to phenotypic variability is elusive, especially in host generalists.

Results

We use 25 high-quality genomes to create a graphical pan-genome of the globally distrib

SUBMITTER: Derbyshire MC 

PROVIDER: S-EPMC12036203 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature