BioCurve Analyzer: a web-based shiny app for analyzing biological response curves.

ABSTRACT:

Background

Dose-response and time-to-event data are common in enzymology, pharmacology, and agronomy studies. Diverse biological response curves can be generated from such data. The features of these curves can be elucidated through parameters such as ED₅₀ (the effective dose that gives 50% of the maximum response) and T₅₀ (the time required to reach 50% of the maximum response). Properly estimating these parameters is crucial for inferring the potency of compounds or the relative timings of biological processes.

Results

We present an open-source Shiny application, BioCurve Analyzer, that simplifies the process of inferring ED₅₀ and T₅₀ parameters from response curves exhibiting various patterns, including classic monotonic sigmoid

SUBMITTER: Xing Z 

PROVIDER: S-EPMC12036208 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature