Acute respiratory infections due to antibiotic-nonsusceptible <i>Streptococcus pneumoniae</i> in United States adults.

ABSTRACT:

Background

We aimed to estimate the burden of antibiotic-nonsusceptible non-bacteremic pneumonia and sinusitis due to Streptococcus pneumoniae (pneumococcus) in US adults (≥18 years).

Methods

We estimated antibiotic-nonsusceptible pneumococcal sinusitis and non-bacteremic pneumonia incidence as products of non-bacteremic pneumococcal pneumonia and sinusitis incidence rates, serotype distribution, and serotype-specific antimicrobial nonsusceptibility prevalences by antibiotic class and guideline-recommended agents from 2016-2019. We derived pneumonia and sinusitis incidence rates from national healthcare utilization surveys and administrative datasets; pneumococcal-attributable attributable percents and serotype distributions from published data; and serotype-specific

SUBMITTER: King LM 

PROVIDER: S-EPMC12036403 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature