Single-cell transcriptomic analysis reveals genome evolution in predatory litostomatean ciliates.

ABSTRACT: Many ciliated protists prey on other large microbial organisms, including other protists and microscopic metazoans. The ciliate class Litostomatea unites both predatory and endosymbiotic species. The evolution of predation ability in ciliates remains poorly understood, in part, due to a lack of genomic data. To fill this gap, we acquired the transcriptome profiles of six predatory litostomateans using single-cell sequencing technology and investigated their transcriptomic features. Our results show that: (1) in contrast to non-predatory ciliates, the predatory litostomateans have expanded gene families associated with transmembrane activity and reactive oxidative stress response pathways, potentially as a result of cellular behaviors such as fast contraction and extension; (2) the expansio

SUBMITTER: Zhou Z 

PROVIDER: S-EPMC12036533 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature