Associations between dementia and exposure to topical glaucoma medications.

ABSTRACT:

Background

Some studies have suggested that glaucoma may be associated with neurodegeneration and a higher risk of dementia.

Objective

To evaluate whether exposure to different categories of topical glaucoma medications is associated with differential dementia risks in people with glaucoma.

Methods

We used data from Adult Changes in Thought, a population-based, prospective cohort study that follows cognitively normal older adults from Kaiser Permanente Washington (KPWA) until Alzheimer's disease (AD) and related dementia development. We included participants with a diagnosis of glaucoma, KPWA pharmacy records of filling topical glaucoma medication (alpha-adrenergic agonists [AAA], beta-adrenergic antagonists, miotics, carbonic anhydrase inhibitors [CAI], and prostagla

SUBMITTER: Davidson O 

PROVIDER: S-EPMC12036566 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature