Distribution status and influencing factors of antibiotic resistance genes in the Chaohu Lake, China.

ABSTRACT:

Background

Chaohu Lake (CL) is one of the most polluted areas in China due to its high content of antibiotics. However, the distribution and influencing factors of antibiotic resistance genes (ARGs) in this lake are still controversial.

Methods

To solve this problem, we used metagenomic sequencing to investigate the distribution and in-fluencing factors of ARGs in CL.

Results

Our findings revealed the existence of nine kinds of ARGs, including 45 specific genes. The most abundant types were multidrug, bacitracin, polymyxin, macrolide lincosamide streptogramin, and aminoglycoside. Multiple microorganisms were undeniable ARG reservoirs, although they were not dominant species in the microbiota. Our results also showed that both the microbiota and physiochemical factors

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12036580 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature