Discovery of additional genomic segments reveals the fluidity of jingmenvirus genomic organization.

ABSTRACT: Jingmenviruses are a distinct group of flavi-like viruses characterized by a genome consisting of four to five segments. Here, we report the discovery of three novel putative jingmenviruses, identified by mining publicly available metagenomics data from mosquito and arachnid samples. Strikingly, these novel jingmenvirus sequences contain up to six genomic segments, with pairs of homologous segments coding for putative structural proteins. Following this discovery, we found an additional homologous segment for two other jingmenvirus genomes, which had gone unnoticed in the initial publications. The presence of a single version of the segments coding for non-structural proteins suggests that we have indeed identified jingmenviruses with infectious units that contain up to six segments. We co

SUBMITTER: Valle C 

PROVIDER: S-EPMC12036656 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature