Waitlisting and liver transplantation for MetALD in the United States: An analysis of the UNOS national registry.

ABSTRACT:

Background and aims

The new steatotic liver disease (SLD) nomenclature introduced metabolic and alcohol-associated liver disease (MetALD), describing the intersection of metabolic dysfunction-associated steatotic liver disease and alcohol-associated liver disease. Waitlisting and liver transplantation for MetALD are not well defined. We aimed to develop and validate an algorithm for identifying SLD phenotypes and assessing trends in waitlisting and transplant outcomes.

Approach and results

We conducted a retrospective cohort study using the United Network for Organ Sharing registry, supplemented with detailed single-center data. We developed 5 candidate algorithms for SLD classification and calculated their diagnostic performance. Trends in waitlist registrations and transpl

SUBMITTER: Ochoa-Allemant P 

PROVIDER: S-EPMC12036730 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature