Bronsted acidic surfactant [HDMM]⁺ [HSO₄]^-: a green microreactor assembly for stereoselective synthesis of novel thiazolyl-pyrazole-chromen-2-ones in water.

ABSTRACT: A novel Brønsted acidic surfactant was synthesized and employed as a catalyst for a one-pot multi-component reaction. Small angle X-ray scattering (SAXS) analysis was performed, which confirmed that the micelles exhibited an average diameter of 3.1 nm and average inter-micellar distance of 0.49 nm. Ground state density functional theory (DFT) calculation was performed on the surfactant molecule to optimize the geometrical structure. A series of novel thiazolyl-pyrazole-chromen-2-one derivatives were efficiently synthesized through a convenient one-pot multi-component reaction of substituted 3-acetoacetyl coumarins, thiosemicarbazide and dialkyl acetylene dicarboxylates in water using a novel hexadecyl methyl morpholinium hydrogen sulfate [HDMM]⁺ [HSO₄]^- as

SUBMITTER: Patil MV 

PROVIDER: S-EPMC12036754 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature