Longitudinal alterations in morphological brain networks and cognitive function in common-type COVID-19: a 3-month follow-up study.

ABSTRACT:

Purpose

To investigate the morphological network and cognitive function of patients with common-type coronavirus disease 2019 (COVID-19) during the acute phase, and examine dynamic changes at 3-month follow-up.

Methods

At baseline, high-resolution T1-weighted imaging was conducted in 35 patients with COVID-19 and 40 healthy controls; 22 patients were reassessed at 3 months. All patients underwent cognitive assessments. Individual morphological brain networks were constructed using grey matter volume similarity, and topological properties were analyzed using graph theory. We used an independent sample t-test at baseline and a paired sample t-test to compare the 3-month follow-up with the acute phase, with false discovery rate corrections (p < 0.05).

Re

SUBMITTER: Liu Y 

PROVIDER: S-EPMC12037390 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature