The predictive value of maternal and neonatal inflammatory biomarkers for necrotizing enterocolitis.

ABSTRACT: More than half of preterm births are triggered by inflammatory processes at the foeto-maternal interface. These inflammatory processes can persist after birth due to the unique vulnerabilities of preterm infants, often resulting in sustained inflammation with a role in complications such as bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC), intraventricular hemorrhage (IVH), and periventricular leukomalacia (PVL). The aim of this study was to evaluate the predictive value of maternal inflammatory status, assessed through biomarkers of inflammation (CRP, chorioamnionitis, preeclampsia), and neonatal inflammatory markers (CRP 1, CRP 2, PCT, IL3, MMP9) on the incidence of NEC in preterm neonates. We conducted a prospective longitudinal study in the 1st Neonatology Department,

SUBMITTER: Matyas M 

PROVIDER: S-EPMC12037420 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature