Global, regional, and national burden of leukemia, 1990-2021: a systematic analysis of the global burden of disease in 2021.

ABSTRACT:

Background

Leukemia is a heterogeneous hematologic malignancy with varying incidence, mortality, and disability-adjusted life years (DALYs) worldwide. Although the burden of leukemia has declined over recent decades, substantial disparities remain across different regions, socioeconomic levels, age groups, and sexes. This study looks at trends in leukemia cases, deaths, and the impact on quality of life from 1990 to 2021, aiming to uncover inequalities and help design better interventions.

Methods

This study extracted data from the Global Burden of Disease (GBD) database (1990-2021) for five types of leukemia. The age-standardized incidence, mortality, and DALY rates for leukemia were calculated for 204 countries and 27 super regions worldwide. The estimated annual percentag

SUBMITTER: Chen J 

PROVIDER: S-EPMC12037485 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature