Characteristics and outcomes in severe and critically ill children with first wave SARS-CoV-2 Omicron infection in Northeast China.

ABSTRACT:

Aim

To describe the characteristics of severe and critically ill children with first-wave SARS-CoV-2 Omicron infection admitted to the pediatric intensive care unit (PICU) at the National Children's Regional Medical Center in Northeast China and to explore factors associated with poor outcomes.

Methods

This observational cohort study was conducted in a PICU in northeastern China and included children under 18 years of age who were severely and critically ill due to SARS-CoV-2 Omicron infection between December 2022 and February 2023. Patients were categorized into two groups: the invasive mechanical ventilation (IMV) group and the non-IMV group. The primary outcome measured was the need for IMV, while secondary outcomes included death or prolonged PICU stay. Univariate and m

SUBMITTER: Sun T 

PROVIDER: S-EPMC12037530 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature