Early-onset neonatal sepsis in a Chinese maternal and child healthcare centre, 2017-2023.

ABSTRACT:

Objective

Early-onset sepsis (EOS) remains an important issue in neonatal units. Characteristics of EOS from China have not been fully revealed yet. Our aim is to investigate epidemiology, microbiology and clinical feature of EOS in a Chinese maternal and child healthcare centre.

Methods

This is a retrospective observational study of EOS infants born in or admitted to Hunan Provincial Maternal and Child Health Care Hospital from January 1, 2017 to December 31, 2023.

Results

During the study period, there were 131 neonatal infections. The incidence of EOS was 1.12 (95% CI 0.94-1.33) per 1,000 live births or 3.85 (95% CI 3.22-4.56) per 1,000 admissions. Coagulase-negative staphylococci (CoNS) (n = 43, 32.3%), group B Streptococcus (GBS) (n = 24, 18.

SUBMITTER: Wang W 

PROVIDER: S-EPMC12037611 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature