Phylogenetic analysis of <i>vp2</i> gene of the infectious bursal disease virus in South China during 2023.

ABSTRACT: Infectious Bursal Disease (IBD) is an acute, highly infectious, immunosuppressive disease caused by the infectious bursal disease virus (IBDV). To elucidate the prevalence of IBDV in southern China, a total of 60 tissues (including spleen and bursa) suspected of IBDV infection were collected from broiler chickens in 2023. In this study, a total of 31 IBDV strains were successfully isolated. The vp2 gene sequences of these isolates were sequenced and analysed. The results showed that 8 of the isolates were identified as very virulent strains, 11 as classical strains and 12 as novel variants. The nucleotide sequence identity among the isolates ranged from 90.7 to 100%, as determined by MegAlign. Further analysis revealed that the novel mutant strains exhibited characteristic amino aci

SUBMITTER: Zhu K 

PROVIDER: S-EPMC12037624 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature