Life's crucial 9 is inversely and linearly associated with female infertility prevalence: a cross-sectional analysis from NHANES 2013-2018.

ABSTRACT: Cardiovascular health (CVH) and depression may be associated with female infertility. More recently, it has been suggested that the addition of psychological health assessment to Life's Essential 8 (LE8), known as Life's Crucial 9 (LC9), may be clinically relevant. We aimed to explore the association of LC9 with female infertility and whether LC9 has significantly improved predictive ability for infertility compared to LE8 through NHANES 2013-2018. The LE8 was assessed by the approach proposed by the American Heart Association and included 8 CVH components. LC9 added an additional assessment of depression score based on the Patient Health Questionnaire-9 to LE8. Female infertility was diagnosed by self-report. Multivariate logistic regression analyses were used to explore these association

SUBMITTER: Li B 

PROVIDER: S-EPMC12037776 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature