Pharmacological interventions for co-occurring psychopathology in people with borderline personality disorder: secondary analysis of the Cochrane systematic review with meta-analyses.

ABSTRACT:

Background

Medications are commonly used to treat co-occurring psychopathology in persons with borderline personality disorder (BPD).

Aims

To systematically review and integrate the evidence of medications for treatment of co-occurring psychopathology in people with BPD, and explore the role of comorbidities.

Method

Building on the current Cochrane review of medications in BPD, an update literature search was done in March 2024. We followed the methods of this Cochrane review, but scrutinised all identified placebo-controlled trials post hoc for reporting of non BPD-specific ('co-occurring') psychopathology, and explored treatment effects in subgroups of samples with and without defined co-occurring disorders. GRADE ratings were done to assess the evidence cert

SUBMITTER: Pereira Ribeiro J 

PROVIDER: S-EPMC12038388 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature