The SAS chromatin-remodeling complex mediates inflorescence-specific chromatin accessibility for transcription factor binding.

ABSTRACT: While the role of transcription factors in flower development is well understood, the impact of chromatin remodeling on this process remains largely unclear. We conducted a comprehensive analysis to investigate the coordination of the SAS, BAS, and MAS-type SWI/SNF chromatin-remodeling complexes with transcription factors to regulate chromatin accessibility and gene transcription during flower development in Arabidopsis thaliana. Our findings indicate that the SAS complex binds to numerous genes related to flower development and is responsible for establishing chromatin accessibility of these genes in inflorescences. In contrast, the BAS and MAS complexes exhibit minimal involvement in regulating the accessibility of these genes. The SAS-bound genomic regions and the SAS-dependent accessib

SUBMITTER: Guo J 

PROVIDER: S-EPMC12038394 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature