Barriers and Opportunities for Cancer Clinical Trials in Low- and Middle-Income Countries.

ABSTRACT:

Importance

Clinical trials represent the gold standard to test the safety and efficacy of new or updated approaches to treatments that will inform quality cancer care. However, cancer trials enroll few patients in low- and middle-income countries (LMICs), are often led by investigators from high-income countries, and do not adequately reflect global disease burden or population diversity.

Objective

To identify key challenges and strategies to advance contextually relevant, quality cancer trials in LMICs.

Design, setting, and participants

The survey used in this survey study was available in English, Arabic, French, Portuguese, and Spanish and was conducted by the US National Cancer Institute from October 18 to December 22, 2023. Clinicians with experience in cancer th

SUBMITTER: Eldridge L 

PROVIDER: S-EPMC12038506 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature