Donor History of Drug Use and Graft Survival in Pediatric Heart Transplant Recipients.

ABSTRACT:

Importance

Older children awaiting a heart transplant (HT) sometimes receive a heart offer from a donor with a history of drug use (HDU). The effect of using such donor hearts on posttransplant survival in pediatric recipients is unclear.

Objective

To assess the association of using hearts from donors with HDU on posttransplant graft survival in pediatric HT recipients.

Design, setting, and participants

For this retrospective cohort study, all pediatric HT recipients (aged <18 years) in the Organ Procurement and Transplantation Network database during January 1, 2000, to December 31, 2020, were identified. Among the recipients who received a heart from a donor with HDU, nearly all donors were aged 11 years or older. A propensity score (PS) model was developed to asses

SUBMITTER: Esteso P 

PROVIDER: S-EPMC12038511 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature