Epidemiological Evaluation of Neuter Status, Sex, and Breed in Dogs With Cystine Uroliths.

ABSTRACT:

Background

The majority of cystine uroliths occur in intact male dogs. Androgen-dependent (Type III) cystinuria is considered the most common cause.

Objectives

Identify dog breeds in which castration is likely to decrease the risk of cystine uroliths, the potential effect of delaying castration on cystine urolith formation, and urolith recurrence frequency.

Animals

Records of 5477 dogs with cystine uroliths and comparison groups without cystine uroliths (263 938 dogs with non-cystine uroliths and 44 491 dogs from a hospital population).

Methods

In this case-control study, odds ratios and 95% confidence intervals (CIs) were calculated to identify breeds where the proportion of intact males with cystine uroliths was higher than that of intact males without cystin

SUBMITTER: Lulich JP 

PROVIDER: S-EPMC12038738 | biostudies-literature | 2025 May-Jun

REPOSITORIES: biostudies-literature