Untargeted metabolomics analysis of the spleens of ducks infected with Clostridium perfringens type A.

ABSTRACT:

Background

The aim of this study was to investigate the metabolomic changes in the spleens of ducks artificially infected with Clostridium perfringens type A. Twenty-four healthy ducks aged 1 d were used for this purpose. After acclimatization for 37 d, the ducks were divided into 4 treatment groups (n = 6): the control group (normal group), infection Group 1 (66 h), infection Group 2 (90 h) and infection Group 3 (114 h). The ducks in the corresponding infection group were challenged with 8 mL of C. perfringens type A bacterial solution (1 × 10⁸ CFU/mL) for 4 days. The experimental ducks were culled at 0 h, 66 h, 90 h and 114 h after infection, and the ducks were sacrificed for spleen sampling at the end of the experiment. Autopsy observations, spleen pathological change

SUBMITTER: Zeng C 

PROVIDER: S-EPMC12039087 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature