Association of non-insulin-based insulin resistance indices, mean platelet volume and prostate cancer: a cross-sectional study.

ABSTRACT:

Purpose

Insulin resistance and prostate cancer (PCa) association results remain controversial. However, few studies have compared the role of various non-insulin-based insulin resistance (NI-IR) indices and mean platelet volume (MPV) in PCa.

Methods

We conducted a cross-sectional study, the case group included 354 patients with PCa, and the control group included 1,498 non-PCa participants. We performed inverse probability weighting to reduce the impact of differences in baseline information between the case and control groups on results. Weighted logistic regression analysis for assessing the relationship between NI-IR indices and PCa risk. Fitting 4-point restricted cubic spline (RCS) plots to show the trend of NI-IR indices with PCa risk. The interaction between insulin r

SUBMITTER: Wang J 

PROVIDER: S-EPMC12039131 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature