Analysis of clinical and microbiological characteristics of invasive Klebsiella pneumoniae liver abscess syndrome.

ABSTRACT:

Background

Invasive Klebsiella pneumoniae liver abscess syndrome (IKPLAS) is emerging as a new disease worldwide, threatening human health. This study aimed to investigate the clinical and microbiological features of IKPLAS in order to detect this syndrome early and select antibiotics appropriately.

Methods

Medical data from patients in Tongji Hospital, China, diagnosed with Klebsiella pneumoniae liver abscess (KPLA) between 2015 and 2023 was collected and analyzed retrospectively.

Results

The study included 208 patients with KPLA, 41 with IKPLAS, and 167 with non-IKPLAS (NIKPLAS). Multivariate logistic regression analysis demonstrated that symptoms in other organ systems (including ocular, pulmonary, and neurological symptoms) (p = 0.001) and a sequential organ failu

SUBMITTER: Gu L 

PROVIDER: S-EPMC12039297 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature