Donor-Related Risk Factors for Normothermic Machine Perfusion in Liver Transplantation: A Meta-Analysis.

ABSTRACT:

Background and aims

During normothermic machine perfusion (NMP), a variety of criteria are used to gauge the suitability of an organ for transplantation. However, the relations between donor factors and these criteria are poorly understood. The aim of this meta-analysis was to investigate the association between donor-related risk factors and the decision to transplant a liver subjected to NMP.

Methods

A comprehensive literature search was performed for articles published up to March 2025 in four databases, reporting livers subjected to NMP for viability assessment prior to transplantation. Effect size (ES) was calculated using Cohen's D and log odds ratio.

Results

Out of 806 unique articles, 18 were included in this meta-analysis, encompassing 690 liver grafts that u

SUBMITTER: den Dekker AMP 

PROVIDER: S-EPMC12039471 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature