Measles Population Immunity in Hunan, China: A Serological Assessment.

ABSTRACT:

Background

Assessing the measles immunity profile is critical for developing effective nationwide or regionwide supplementary immunization activities (SIAs). This study aims to assess measles population immunity levels in China and investigate factors contributing to age-specific heterogeneities.

Methods

We conducted a cross-sectional population-based serological study in southern China between June and October 2021. We determined the population mean antibody concentration and seroprevalence by age and over time, along with their associated determinants. Moreover, we estimated the contact-adjusted immunity levels by considering both age-specific immunity levels and population contact rates.

Results

Among the 1015 study participants (aged 0-95 years), the overall serop

SUBMITTER: Wu Y 

PROVIDER: S-EPMC12039485 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature