Volume-targeted on high-frequency oscillatory ventilation in preterm infants: a systematic review.

ABSTRACT:

Objective

This systematic review aimed to analyze, in neonates, the effects of high-frequency oscillatory ventilation (HFOV) with volume-targeted (VT) compared with conventional HFOV.

Sources

The authors searched PubMed, EMBASE, Cochrane, and ClinicalTrials.gov from inception until August 4th, 2024, to identify studies comparing HFOV with and without VT in neonates under 44 weeks corrected age. Outcomes analyzed were VThf, amplitude and carbon dioxide partial pressure (PCO₂) variability, episodes of hypoxemia, hypocarbia or hypercarbia, duration of mechanical ventilation, rates of bronchopulmonary dysplasia (BPD) or intraventricular hemorrhage (IVH), and mortality. ROB-2 and ROBINS were used for risk of bias assessment.

Summary of the findings

This systemat

SUBMITTER: Orlandin EAS 

PROVIDER: S-EPMC12039505 | biostudies-literature | 2025 May-Jun

REPOSITORIES: biostudies-literature