Efficacy of traditional Chinese medicine-based clearing heat and laxative method against nonalcoholic fatty liver disease: A systematic review and meta-analysis.

ABSTRACT:

Background

Increasing evidences support the effectiveness of traditional Chinese medicine (TCM) in the treatment of nonalcoholic fatty liver disease (NAFLD), but it involves a wide variety of therapeutic methods. We aimed to evaluate the efficacy and safety of the TCM-based clearing heat and laxative (CHL) Method for intervention in NAFLD.

Methods

Randomized controlled trials (RCTs) of CHL method for NAFLD were included. We searched Pubmed, Scopus, Web of science, CNKI, CBM, VIP, Wanfang databases from the inception to October 2023. We performed separate meta-analyses of clinical outcomes for liver enzymes, lipid profile, and total efficiency. The quality of the evidence was assessed with the Cochrane risk of bias tool. This study is registered on INPLASY, number INPLASY2022

SUBMITTER: Qu YN 

PROVIDER: S-EPMC12039999 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature