Survival assessment and pre-diagnostic risk factors for lung cancer incidence: Insights from the Golestan Cohort Study.

ABSTRACT:

Background

Lung cancer remains a pressing health issue globally. This study investigates survival rates and the impact of pre-diagnostic factors on lung cancer incidence in Golestan Cohort Study (GCS).

Method

The GCS, initiated in 2004 with enrollment concluding in 2008, comprises 49,783 individuals aged 40-75 from the Golestan province in northeastern Iran. Our analysis included all cases of lung, tracheal, and bronchial cancers diagnosed under ICD-10 codes C33-C34 from the study's inception to 2022, tracking participants until death. A sensitivity analysis, excluding lung cancer cases diagnosed within the initial 24 months of follow-up, was performed to address the reverse causation bias from previously undiagnosed conditions at baseline.

Results

Out of 49,783 parti

SUBMITTER: Mousavi SF 

PROVIDER: S-EPMC12040151 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature