Handheld Point-of-Care Devices for Snakebite Coagulopathy: A Scoping Review.

ABSTRACT: Venom-induced consumption coagulopathy (VICC) is a common complication of snakebite that is associated with hypofibrinogenemia, bleeding, disability, and death. In remote tropical settings, where most snakebites occur, the 20-minute whole blood clotting test is used to diagnose VICC. Point-of-care (POC) coagulation devices could provide an accessible means of detecting VICC that is better standardized, quantifiable, and more accurate. In this scoping review, the mechanistic reasons that previously studied POC devices have failed in VICC are considered, and evidence-based recommendations are made to prioritize certain devices for clinical validation studies. Four small studies have evaluated a POC international normalized ratio (INR) device in patients with Australian Elapid, Daboia russ

SUBMITTER: Abouyannis M 

PROVIDER: S-EPMC12040437 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature