Aptamer-functionalized graphene quantum dots combined with artificial intelligence detect bacteria for urinary tract infections.

ABSTRACT:

Objectives

Urinary tract infection is one of the most prevalent forms of bacterial infection, and prompt and efficient identification of pathogenic bacteria plays a pivotal role in the management of urinary tract infections. In this study, we propose a novel approach utilizing aptamer-functionalized graphene quantum dots integrated with an artificial intelligence detection system (AG-AI detection system) for rapid and highly sensitive detection of Escherichia coli (E. coli).

Methods

Firstly, graphene quantum dots were modified with the aptamer that can specifically recognize and bind to E. coli. Therefore, the fluorescence intensity of graphene quantum dots was positively correlated with the concentration of E. coli. Finally, the fluorescence imag

SUBMITTER: Li K 

PROVIDER: S-EPMC12040687 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature