Case Report: Giant cell lesions in the Maxillofacial region: diagnostic points and treatment strategies.

ABSTRACT:

Objective

Giant cell-rich lesions in the maxillofacial region are relatively rare, and comprehensive clinical differential diagnostic protocols are currently lacking. This article aims to provide a reference for the clinical diagnosis and treatment of giant cell-rich lesions.

Methods

This study investigates the distinguishing features of four types of giant cell-rich lesions in differential diagnosis and treatment: giant cell tumor of bone (GCT), aneurysmal bone cyst (ABC), tenosynovial giant cell tumor (TGCT), and giant cell reparative granuloma (GCRG).

Results

Immunohistochemical (IHC) analysis reveals strong p63 positivity in the mononuclear stromal cells of GCT, but not in GCRG. The "fluid-fluid level" observed in magnetic resonance imaging (MRI) is a diagnostic i

SUBMITTER: Gao X 

PROVIDER: S-EPMC12040924 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature